Non Small Cell Lung Cancer — Expanded Access Programs
Overview
Right2Hope maintains a directory of 262 expanded access programs, clinical trials, and compassionate use pathways listed for Non Small Cell Lung Cancer. Each entry below was sourced from sponsor disclosures and public clinical-trial registries. Use this hub to understand the breadth of ongoing research, identify sponsors with non small cell lung cancer programs, and link out to specific protocols for eligibility, contact, and request details. Of these, 204 programs are currently active or recruiting, with the remaining 58 in other lifecycle stages. Sponsors actively running programs in this area include AstraZeneca, Memorial Sloan Kettering Cancer Center, Hoffmann-La Roche, Merck Sharp & Dohme LLC, AbbVie, and others.
By recruiting status
Snapshot of where every Non Small Cell Lung Cancer program currently sits in its lifecycle.
- Active / Recruiting204
- Inactive58
Top sponsors
Organisations running the most Non Small Cell Lung Cancer programs in the directory.
- AstraZeneca19 programs
- Memorial Sloan Kettering Cancer Center15 programs
- Hoffmann-La Roche12 programs
- Merck Sharp & Dohme LLC12 programs
- AbbVie5 programs
- Bristol-Myers Squibb5 programs
- H. Lee Moffitt Cancer Center and Research Institute5 programs
- Pfizer5 programs
- Daiichi Sankyo4 programs
- M.D. Anderson Cancer Center4 programs
Non Small Cell Lung Cancer programs (showing 120 of 262)
Sorted by recruiting status, then alphabetically by program name. Click any program to view eligibility, locations, and sponsor contact details.
- Study on MK-1084 and Other Treatments for Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study on Pembrolizumab and Berahyaluronidase Alfa for Treating Newly Diagnosed Metastatic Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study on Intismeran (V940) With or Without Pembrolizumab for High-Risk Stage I Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study on Calderasib and Durvalumab for Treating Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study on Investigational Combination Therapy with BNT326 and BNT327 for Advanced Non-Small Cell Lung Cancer (NSCLC) — BioNTech SE
- First-in-Human Study of CKD-703 for Advanced Solid Tumors and Non-Small Cell Lung Cancer — Chong Kun Dang Pharmaceutical
- First Human Trial of BLU-924 for Advanced Cancers with KRAS Mutations — Blueprint Medicines Corporation
- Global Study on Rilvegostomig or Pembrolizumab with Chemotherapy for First-Line Treatment of Metastatic Squamous Non-Small Cell Lung Cancer — AstraZeneca
- Global Study on Durvalumab and Domvanalimab After Chemoradiation for Stage III Unresectable Non-Small Cell Lung Cancer (NSCLC) — AstraZeneca
- Global Study on Durvalumab with Oleclumab or Monalizumab After Chemoradiation for Stage III Unresectable Non-Small Cell Lung Cancer — AstraZeneca
- Global Study on Osimertinib for Patients with Early-Stage EGFR-Mutated Non-Small Cell Lung Cancer After Tumor Removal — AstraZeneca
- Study on the Safety and Effectiveness of ENV-501 for Patients with HER3-Positive Solid Tumors — Endeavor Biomedicines, Inc.
- Study on CLN-081 for Patients with Non-Small Cell Lung Cancer — Cullinan Therapeutics Inc.
- Study on VS-7375 for Patients with KRAS G12D-Mutated Solid Tumors — Verastem, Inc.
- Phase 2 Study on Immunotherapy for Non-Small Cell Lung Cancer Resistant to Previous Treatments — M.D. Anderson Cancer Center
- Phase 2 Study of Adding Vitamin C to Chemotherapy and Radiation for Non-Small Cell Lung Cancer — Joseph J. Cullen, MD, FACS
- Phase 2 Study of Osimertinib and Selumetinib for Advanced EGFR Mutant Lung Cancer — Dana-Farber Cancer Institute
- Phase 2 Study of VS-7375 for Patients with KRAS G12D-Mutated Non-Small Cell Lung Cancer — Verastem, Inc.
- Phase 2 Study of Zanidatamab for Patients with HER2-positive Tumors — Jazz Pharmaceuticals
- Phase II Study of HLX43 for Advanced Non-Small Cell Lung Cancer (NSCLC) — Shanghai Henlius Biotech
- Phase III Study of Dato-DXd and Rilvegostomig for Stage I Adenocarcinoma NSCLC After Tumor Removal — AstraZeneca
- Study Comparing Savolitinib and Osimertinib with Savolitinib and Placebo in Patients with Advanced Lung Cancer — AstraZeneca
- Study on FMC-376 for Patients with KRAS G12C Mutated Advanced Solid Tumors — Frontier Medicines Corporation
- Study on Combining Immunotherapy and Radiotherapy for Non-Small Cell Lung Cancer — University of Chicago
- Study Comparing Divarasib and Pembrolizumab with Standard Chemotherapy for Advanced KRAS G12C-Mutated Lung Cancer — Hoffmann-La Roche
- Study Comparing Divarasib with Sotorasib or Adagrasib for Treating Advanced KRAS G12C-positive Lung Cancer — Hoffmann-La Roche
- Study on the Effectiveness and Safety of Different Treatments for Stage III Non-Small Cell Lung Cancer — Hoffmann-La Roche
- Study on the Safety and Effects of Divarasib with Other Cancer Treatments for Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation — Hoffmann-La Roche
- Study on Abemaciclib for Patients with Previously Treated KRAS Mutated Lung Cancer — Eli Lilly and Company
- Study on BIO 300 and Chest Radiation Therapy for People with Non-Small Cell Lung Cancer and Interstitial Lung Disease — Memorial Sloan Kettering Cancer Center
- Study on BMS-986340 Alone and with Nivolumab or Docetaxel for Advanced Solid Tumors — Bristol-Myers Squibb
- Study on Cemiplimab with Chemotherapy and Other Treatments for Adults with Operable Non-Small Cell Lung Cancer — Regeneron Pharmaceuticals
- A Study of DSP107 Alone and in Combination With Atezolizumab for Patients With Advanced Solid Tumors — Kahr Medical
- Study Comparing DZD9008 with Standard Chemotherapy for Advanced Non-Small Cell Lung Cancer — Dizal Pharmaceuticals
- Study on GV20-0251 Alone and with Pembrolizumab for Treating Solid Tumor Cancers — GV20 Therapeutics
- Study on IBI363 for Patients with Advanced Solid Tumors — Innovent Biologics (Suzhou) Co. Ltd.
- Study on Ivonescimab with Dato-DXd or Osimertinib for Non-Small Cell Lung Cancer — Memorial Sloan Kettering Cancer Center
- Study on Ivonescimab for Treating Non-Small Cell Lung Cancer — Memorial Sloan Kettering Cancer Center
- Study on Ivonescimab, Chemotherapy, and Stereotactic Radiosurgery for People with Non-Small Cell Lung Cancer — Memorial Sloan Kettering Cancer Center
- Study on Lorlatinib and Ramucirumab Combination for Lung Cancer — Memorial Sloan Kettering Cancer Center
- Study of MK-1084 and Pembrolizumab for Treating KRAS G12C Mutant, Metastatic Non-small Cell Lung Cancer with High PD-L1 Levels — Merck Sharp & Dohme LLC
- Study on Multiple Treatments for Patients with Certain Biomarkers and Resectable Stages IB-III Non-Small Cell Lung Cancer — Genentech, Inc.
- Study on Durvalumab and Chemotherapy Before and After Surgery for Treating Resectable Non-small Cell Lung Cancer — AstraZeneca
- Study on New Treatment Combinations for Non-Small Cell Lung Cancer (NSCLC) — AstraZeneca
- Study on OR502, a Monoclonal Antibody Targeting LILRB2, Alone and with Other Cancer Treatments — OncoResponse, Inc.
- Study on Oral Alintegimod with Ipilimumab and Nivolumab for Cancer Treatment — 7 Hills Pharma, LLC
- Study on Osimertinib With or Without Chemotherapy for First-Line Treatment in Patients with EGFR-Mutated Non-Small Cell Lung Cancer — AstraZeneca
- Study on Osimertinib With or Without Chemotherapy Compared to Chemotherapy Alone for Treating EGFRm Positive Non-Small Cell Lung Cancer Before Surgery — AstraZeneca
- Study on Patient Preference for Subcutaneous vs. Intravenous Pembrolizumab in Various Cancers — Merck Sharp & Dohme LLC
- Study on Pembrolizumab With or Without Chemotherapy and Additional Treatments for Advanced Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study on Selpercatinib (LOXO-292) for Advanced Solid Tumors, RET Fusion-Positive Tumors, and Medullary Thyroid Cancer — Loxo Oncology, Inc.
- Study on Targeted Radiation Therapy for People with Metastatic Non-Small Cell Lung Cancer (NSCLC) — Memorial Sloan Kettering Cancer Center
- Study on Tislelizumab with New Treatments for Non-Small Cell Lung Cancer — BeiGene
- Study on Trastuzumab Deruxtecan for People with Non-Small Cell Lung Cancer — Memorial Sloan Kettering Cancer Center
- Study of V940 Plus Pembrolizumab Versus Placebo Plus Pembrolizumab in Patients with Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study Comparing Valemetostat Tosylate and Pembrolizumab with Pembrolizumab Alone for First-Line Treatment of NSCLC Without Specific Genetic Changes — Daiichi Sankyo
- Study on the Safety and Effects of Telisotuzumab Vedotin for Previously Treated Non-Squamous Non-Small Cell Lung Cancer — AbbVie
- Study Comparing IV Telisotuzumab Vedotin and IV Docetaxel in Adults with Previously Treated Non-Squamous Non-Small Cell Lung Cancer — AbbVie
- Study on Pembrolizumab With or Without Sacituzumab Tirumotecan for Treating Non-Small Cell Lung Cancer After Surgery — Merck Sharp & Dohme LLC
- Study on the Effectiveness of WSD0922-FU in Patients with Advanced Non-Small Cell Lung Cancer with C797S Mutation — Wayshine Biopharm, Inc.
- Study Comparing Nivolumab and Relatlimab with Chemotherapy to Pembrolizumab with Chemotherapy for Advanced Non-squamous Non-small Cell Lung Cancer — Bristol-Myers Squibb
- Study Comparing Chemotherapy Plus Osimertinib to Chemotherapy Plus Placebo in Patients with Non-Small Cell Lung Cancer (NSCLC) — AstraZeneca
- Study on the Effectiveness and Safety of Divarasib Compared to Immunotherapy or Observation in Patients with Resected Stage II-III KRAS G12C-Positive Non-Small Cell Lung Cancer — Hoffmann-La Roche
- Study on the Effectiveness and Safety of Targeted Therapies for Non-Small Cell Lung Cancer (NSCLC) — Hoffmann-La Roche
- A Study to Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC — Teligene US
- Study on the Safety and Effectiveness of A2B530 CAR T-Cell Therapy for Solid Tumors with CEA Expression and HLA-A*02 Loss — A2 Biotherapeutics Inc.
- Study on the Safety and Effectiveness of A2B694 CAR T-Cell Therapy for Solid Tumors with MSLN Expression and HLA-A*02 Loss — A2 Biotherapeutics Inc.
- Study on Two Dosing Methods of Nivolumab with Ipilimumab and Chemotherapy for Untreated Metastatic or Recurrent Non-Small Cell Lung Cancer — Bristol-Myers Squibb
- Study on ANS02 for Patients with EGFR Mutation-Positive Non-Small Cell Lung Cancer — Avistone Biotechnology Co., Ltd.
- Study on the Safety of AZD6750 for Adults with Advanced or Metastatic Solid Tumors — AstraZeneca
- Study on PF-08634404 with Chemotherapy for Adults with Advanced or Metastatic Non-Small Cell Lung Cancer — Pfizer
- Study on How Fianlimab with Cemiplimab and Chemotherapy Works Compared to Cemiplimab and Chemotherapy for Treating Advanced Non-Small Cell Lung Cancer — Regeneron Pharmaceuticals
- Study on Adagrasib and SRS for Patients with KRAS G12C-Mutated Lung Cancer with Untreated Brain Metastases — Ryan Gentzler, MD
- Study on Using Genetically Modified T-Cells to Target Cancer Mutations in People with Metastatic Cancer — National Cancer Institute (NCI)
- Study on Amivantamab with Tyrosine Kinase Inhibitors for Advanced Non-Small Cell Lung Cancer with ALK, ROS1, or RET Alterations — University of Colorado, Denver
- Expanded Access Program for Zipalertinib in Advanced Non-Small Cell Lung Cancer — Taiho Oncology, Inc.
- Study on Oral EGFR Inhibitor Sunvozertinib for Advanced Non-Small Cell Lung Cancer with EGFR or HER2 Mutation — Dizal Pharmaceuticals
- Study on Entrectinib for Treating Solid Tumors with Specific Gene Changes — Hoffmann-La Roche
- Study on Zongertinib for Treating Surgically Removed Non-Small Cell Lung Cancer with HER2 Mutations — Boehringer Ingelheim
- Study on Low-Dose Radiation, Ipilimumab, and Nivolumab Before Surgery for Non-Small Cell Lung Cancer — Brown University
- Study on Cabozantinib for Patients with Specific Gene Changes in Advanced Non-Small Cell Lung Cancer — Memorial Sloan Kettering Cancer Center
- Study on CAN-2409 Plus Prodrug with Standard Immune Therapy for Advanced Lung Cancer — Candel Therapeutics, Inc.
- Study on Carboplatin, Paclitaxel, and Ramucirumab for Non-Small Cell Lung Cancer After Pemetrexed or Pembrolizumab Maintenance — Abramson Cancer Center at Penn Medicine
- Study on Ivonescimab for First-line Treatment of Advanced Squamous Non-small Cell Lung Cancer — Summit Therapeutics
- Study on Ivonescimab for Initial Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) with High PD-L1 Levels — Summit Therapeutics
- Study on Using a Blood Test to Predict Treatment Response and Detect Remaining Cancer in Non-Small Cell Lung Cancer — University of Miami
- Study for Continued Access to Dabrafenib and/or Trametinib Treatment — Novartis Pharmaceuticals
- Study on Whether Durvalumab and Radiation Therapy Can Slow Down Non-Small Cell Lung Cancer — Memorial Sloan Kettering Cancer Center
- DISCERN: Comparing Two Immune Therapy Combinations for PD-L1 Negative Non-Small Cell Lung Cancer — University of Alabama at Birmingham
- Study on Reduced Dose Chemotherapy for Lung Cancer Patients with Other Health Conditions — Fox Chase Cancer Center
- Study on MDX2001 for Patients with Advanced Solid Tumors — ModeX Therapeutics, An OPKO Health Company
- Study on Mavrostobart (PT199) Alone and with Other Cancer Treatments (MORNINGSTAR Study) — Phanes Therapeutics
- Study on Lower Dose 3-Session Radiation Therapy for Lung Cancer Near the Center of the Chest — Yale University
- Study on DRP-104 for Patients with Specific Genetic Changes in Non-Small Cell Lung Cancer — NYU Langone Health
- Early Access Program for HER2/HER3 Bispecific Antibody MCLA-128 for Patients with Advanced NRG1-Fusion Positive Solid Tumors — Merus N.V.
- Study on How the Timing of Immunotherapy Infusions Affects Treatment in Solid Tumors — UNC Lineberger Comprehensive Cancer Center
- Study on the Effectiveness and Safety of Olvimulogene Nanivacirepvec with Chemotherapy and Immune Therapy Compared to Docetaxel in Non-Small Cell Lung Cancer (NSCLC) — Genelux Corporation
- Study on Pembrolizumab with Chemotherapy Before and After Surgery for Treatable Stage II, IIIA, and IIIB Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study on AL3818 and Nivolumab for Treating Advanced Solid Tumors — Sarcoma Oncology Research Center, LLC
- Study Comparing Ensartinib to Crizotinib in ALK Positive Non-Small Cell Lung Cancer Patients — Xcovery Holdings, Inc.
- Expanded Access for Treating Cancers with RET Activation — Eli Lilly and Company
- Access Program for Neladalkib (NVL-655) for Patients with Advanced ALK+ Lung Cancer — Nuvalent Inc.
- Access to ABBV-400 Before Official Approval — AbbVie
- Expanded Access to Ensartinib for Patients with ALK+ Non-Small Cell Lung Cancer — Xcovery Holdings, Inc.
- Expanded Access to Ulixertinib (BVD-523) in Patients with Advanced MAPK Pathway-Altered Malignancies — xCures
- Study on EZH2 Inhibitor Tulmimetostat and PD-1 Blockade for Advanced Non-Small Cell Lung Cancer — VA Office of Research and Development
- Study on the Safety and Effectiveness of TUB-040 for Ovarian and Non-Small Cell Lung Cancer — Tubulis GmbH
- First-In-Human Study of STX-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations — Scorpion Therapeutics, Inc.
- Study on FOG-001 for Advanced or Metastatic Solid Tumors — Fog Pharmaceuticals, Inc.
- Study on GI-101 Alone or with Pembrolizumab, Lenvatinib, or Local Radiotherapy for Advanced Solid Tumors — GI Innovation, Inc.
- Study on Using Stereotactic Body Radiotherapy (SBRT) with Standard Treatment for Cancer That Has Spread — Memorial Sloan Kettering Cancer Center
- Study on IPH5201 and Durvalumab for Patients with Resectable Non-Small Cell Lung Cancer (MATISSE) — Innate Pharma
- JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer — University of Texas Southwestern Medical Center
- Lorlatinib Continuation Study — Pfizer
- Study on MPDL3280A with Chemotherapy and Radiation for Lung Cancer — M.D. Anderson Cancer Center
- Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer — Dana-Farber Cancer Institute
- Study on Neladalkib (NVL-655) for Patients with Untreated Advanced ALK-Positive Non-Small Cell Lung Cancer — Nuvalent Inc.
- Study on Pre-Surgery and Post-Surgery Treatment for Resectable Non-Small Cell Lung Cancer — AstraZeneca
- Study on Cemiplimab Before Surgery for Treating Resectable Lung, Liver, and Head and Neck Cancers in Adults — Regeneron Pharmaceuticals
- Study on Neoadjuvant Dupilumab and Cemiplimab for Early-stage Resectable Non-Small Cell Lung Cancer (NSCLC) — Icahn School of Medicine at Mount Sinai
Looking for a program not shown above? Search the full catalog for “Non Small Cell Lung Cancer” to see every match including additional filters.
About this hub
Expanded access programs (sometimes called compassionate use, named-patient programs, or pre-approval access) allow patients with serious or life-threatening conditions such as Non Small Cell Lung Cancer to receive an investigational therapy outside of a controlled clinical trial when no comparable approved option is available. Eligibility, location, and the application process differ for each program — review the individual program pages below for sponsor contact information, inclusion criteria, and the request workflow. Right2Hope is a 501(c)(3) nonprofit and provides this directory free of charge for patients, caregivers, and treating physicians.
Looking for a different condition? Browse the full Cancer Type hub directory or search the full expanded access program catalog.
