Non-Small-Cell Lung Cancer — Expanded Access Programs
Overview
Right2Hope maintains a directory of 258 expanded access programs, clinical trials, and compassionate use pathways listed for Non-Small-Cell Lung Cancer. Each entry below was sourced from sponsor disclosures and public clinical-trial registries. Use this hub to understand the breadth of ongoing research, identify sponsors with non-small-cell lung cancer programs, and link out to specific protocols for eligibility, contact, and request details. Of these, 105 programs are currently active or recruiting, with the remaining 153 in other lifecycle stages. Sponsors actively running programs in this area include AstraZeneca, Memorial Sloan Kettering Cancer Center, Merck Sharp & Dohme LLC, Hoffmann-La Roche, AbbVie, and others.
By recruiting status
Snapshot of where every Non-Small-Cell Lung Cancer program currently sits in its lifecycle.
- Active / Recruiting105
- Inactive153
Top sponsors
Organisations running the most Non-Small-Cell Lung Cancer programs in the directory.
- AstraZeneca19 programs
- Memorial Sloan Kettering Cancer Center15 programs
- Merck Sharp & Dohme LLC12 programs
- Hoffmann-La Roche11 programs
- AbbVie5 programs
- Bristol-Myers Squibb5 programs
- H. Lee Moffitt Cancer Center and Research Institute5 programs
- Pfizer5 programs
- Daiichi Sankyo4 programs
- M.D. Anderson Cancer Center4 programs
Non-Small-Cell Lung Cancer programs (showing 120 of 258)
Sorted by recruiting status, then alphabetically by program name. Click any program to view eligibility, locations, and sponsor contact details.
- Study on MK-1084 and Other Treatments for Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study on Intismeran (V940) With or Without Pembrolizumab for High-Risk Stage I Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study on Calderasib and Durvalumab for Treating Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study on Investigational Combination Therapy with BNT326 and BNT327 for Advanced Non-Small Cell Lung Cancer (NSCLC) — BioNTech SE
- First-in-Human Study of CKD-703 for Advanced Solid Tumors and Non-Small Cell Lung Cancer — Chong Kun Dang Pharmaceutical
- First Human Trial of BLU-924 for Advanced Cancers with KRAS Mutations — Blueprint Medicines Corporation
- Study on the Safety and Effectiveness of ENV-501 for Patients with HER3-Positive Solid Tumors — Endeavor Biomedicines, Inc.
- Study on VS-7375 for Patients with KRAS G12D-Mutated Solid Tumors — Verastem, Inc.
- Phase 2 Study on Immunotherapy for Non-Small Cell Lung Cancer Resistant to Previous Treatments — M.D. Anderson Cancer Center
- Phase 2 Study of Osimertinib and Selumetinib for Advanced EGFR Mutant Lung Cancer — Dana-Farber Cancer Institute
- Phase 2 Study of VS-7375 for Patients with KRAS G12D-Mutated Non-Small Cell Lung Cancer — Verastem, Inc.
- Phase 2 Study of Zanidatamab for Patients with HER2-positive Tumors — Jazz Pharmaceuticals
- Phase II Study of HLX43 for Advanced Non-Small Cell Lung Cancer (NSCLC) — Shanghai Henlius Biotech
- Phase III Study of Dato-DXd and Rilvegostomig for Stage I Adenocarcinoma NSCLC After Tumor Removal — AstraZeneca
- Study Comparing Savolitinib and Osimertinib with Savolitinib and Placebo in Patients with Advanced Lung Cancer — AstraZeneca
- Study on Combining Immunotherapy and Radiotherapy for Non-Small Cell Lung Cancer — University of Chicago
- Study Comparing Divarasib and Pembrolizumab with Standard Chemotherapy for Advanced KRAS G12C-Mutated Lung Cancer — Hoffmann-La Roche
- Study on the Safety and Effects of Divarasib with Other Cancer Treatments for Advanced Non-Small Cell Lung Cancer with KRAS G12C Mutation — Hoffmann-La Roche
- Study on Abemaciclib for Patients with Previously Treated KRAS Mutated Lung Cancer — Eli Lilly and Company
- Study on BIO 300 and Chest Radiation Therapy for People with Non-Small Cell Lung Cancer and Interstitial Lung Disease — Memorial Sloan Kettering Cancer Center
- Study on Cemiplimab with Chemotherapy and Other Treatments for Adults with Operable Non-Small Cell Lung Cancer — Regeneron Pharmaceuticals
- Study on Ivonescimab with Dato-DXd or Osimertinib for Non-Small Cell Lung Cancer — Memorial Sloan Kettering Cancer Center
- Study on Ivonescimab for Treating Non-Small Cell Lung Cancer — Memorial Sloan Kettering Cancer Center
- Study on Ivonescimab, Chemotherapy, and Stereotactic Radiosurgery for People with Non-Small Cell Lung Cancer — Memorial Sloan Kettering Cancer Center
- Study on Durvalumab and Chemotherapy Before and After Surgery for Treating Resectable Non-small Cell Lung Cancer — AstraZeneca
- Study on New Treatment Combinations for Non-Small Cell Lung Cancer (NSCLC) — AstraZeneca
- Study on Osimertinib With or Without Chemotherapy for First-Line Treatment in Patients with EGFR-Mutated Non-Small Cell Lung Cancer — AstraZeneca
- Study on Osimertinib With or Without Chemotherapy Compared to Chemotherapy Alone for Treating EGFRm Positive Non-Small Cell Lung Cancer Before Surgery — AstraZeneca
- Study on Pembrolizumab With or Without Chemotherapy and Additional Treatments for Advanced Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study on Tepotinib and Osimertinib for Treating MET Amplified Non-Small Cell Lung Cancer After Osimertinib Relapse — EMD Serono Research & Development Institute, Inc.
- Study on Trastuzumab Deruxtecan for People with Non-Small Cell Lung Cancer — Memorial Sloan Kettering Cancer Center
- Study on the Safety and Effects of Telisotuzumab Vedotin for Previously Treated Non-Squamous Non-Small Cell Lung Cancer — AbbVie
- Study on the Effectiveness of WSD0922-FU in Patients with Advanced Non-Small Cell Lung Cancer with C797S Mutation — Wayshine Biopharm, Inc.
- Study Comparing Chemotherapy Plus Osimertinib to Chemotherapy Plus Placebo in Patients with Non-Small Cell Lung Cancer (NSCLC) — AstraZeneca
- Study on the Safety and Effectiveness of A2B530 CAR T-Cell Therapy for Solid Tumors with CEA Expression and HLA-A*02 Loss — A2 Biotherapeutics Inc.
- Study on Two Dosing Methods of Nivolumab with Ipilimumab and Chemotherapy for Untreated Metastatic or Recurrent Non-Small Cell Lung Cancer — Bristol-Myers Squibb
- Study on ANS02 for Patients with EGFR Mutation-Positive Non-Small Cell Lung Cancer — Avistone Biotechnology Co., Ltd.
- Study on the Safety of AZD6750 for Adults with Advanced or Metastatic Solid Tumors — AstraZeneca
- Study on PF-08634404 with Chemotherapy for Adults with Advanced or Metastatic Non-Small Cell Lung Cancer — Pfizer
- Expanded Access Program for Zipalertinib in Advanced Non-Small Cell Lung Cancer — Taiho Oncology, Inc.
- Study on Oral EGFR Inhibitor Sunvozertinib for Advanced Non-Small Cell Lung Cancer with EGFR or HER2 Mutation — Dizal Pharmaceuticals
- Study on Entrectinib for Treating Solid Tumors with Specific Gene Changes — Hoffmann-La Roche
- Study on Zongertinib for Treating Surgically Removed Non-Small Cell Lung Cancer with HER2 Mutations — Boehringer Ingelheim
- Study on CAN-2409 Plus Prodrug with Standard Immune Therapy for Advanced Lung Cancer — Candel Therapeutics, Inc.
- Study on Ivonescimab for Initial Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) with High PD-L1 Levels — Summit Therapeutics
- Study on Using a Blood Test to Predict Treatment Response and Detect Remaining Cancer in Non-Small Cell Lung Cancer — University of Miami
- Study on Whether Durvalumab and Radiation Therapy Can Slow Down Non-Small Cell Lung Cancer — Memorial Sloan Kettering Cancer Center
- DISCERN: Comparing Two Immune Therapy Combinations for PD-L1 Negative Non-Small Cell Lung Cancer — University of Alabama at Birmingham
- Study on Mavrostobart (PT199) Alone and with Other Cancer Treatments (MORNINGSTAR Study) — Phanes Therapeutics
- Study on MEDI4736 for Patients with Completely Removed Non-Small Cell Lung Cancer — Canadian Cancer Trials Group
- Study on DRP-104 for Patients with Specific Genetic Changes in Non-Small Cell Lung Cancer — NYU Langone Health
- Study on Pembrolizumab with Chemotherapy Before and After Surgery for Treatable Stage II, IIIA, and IIIB Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study on AL3818 and Nivolumab for Treating Advanced Solid Tumors — Sarcoma Oncology Research Center, LLC
- Study Comparing Ensartinib to Crizotinib in ALK Positive Non-Small Cell Lung Cancer Patients — Xcovery Holdings, Inc.
- Access Program for Neladalkib (NVL-655) for Patients with Advanced ALK+ Lung Cancer — Nuvalent Inc.
- Expanded Access Program for Zidesamtinib (NVL-520) in Patients with Advanced ROS1+ Non-Small Cell Lung Cancer — Nuvalent Inc.
- Study on FOG-001 for Advanced or Metastatic Solid Tumors — Fog Pharmaceuticals, Inc.
- Study on MPDL3280A with Chemotherapy and Radiation for Lung Cancer — M.D. Anderson Cancer Center
- Study on Neladalkib (NVL-655) for Patients with Untreated Advanced ALK-Positive Non-Small Cell Lung Cancer — Nuvalent Inc.
- Study on Nivolumab, Alone or with Ipilimumab, Before Surgery for Resectable Non-Small Cell Lung Cancer (NSCLC) — Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- Study on Osimertinib and Gefitinib for Untreated Advanced EGFR Mutant Lung Cancer — Dana-Farber Cancer Institute
- Study on Patient Preference for Subcutaneous vs. Intravenous Immune Therapy — Diwakar Davar
- Study on Pembrolizumab and Vorinostat for Patients with Advanced Stage IV Non-Small Cell Lung Cancer — H. Lee Moffitt Cancer Center and Research Institute
- Study on Gavo-cel (TC-210) for Treating Advanced Cancers with Mesothelin Expression — TCR2 Therapeutics
- Phase 1/2 Study of S241656 for Cancers with Specific RAS/MAPK Mutations — Institut de Recherches Internationales Servier
- Study on the Safety and Effectiveness of ST-067 in Patients with Advanced Solid Tumors — Simcha IL-18, Inc.
- Phase 2 Study of Fingolimod for Lung Cancer Treatment — Medical University of South Carolina
- Phase I/II Study of Nivolumab and Ipilimumab Combined with Nintedanib for Non-Small Cell Lung Cancer — H. Lee Moffitt Cancer Center and Research Institute
- Phase II Study of New Cancer Treatments for NSCLC Patients Who Didn't Respond to Anti-PD-1/PD-L1 Therapy — AstraZeneca
- Phase III Study of Osimertinib With or Without Datopotamab Deruxtecan for Advanced Non-small Cell Lung Cancer — AstraZeneca
- Study on JDQ443 Combination Therapy for Advanced Solid Tumors with KRAS G12C Mutation — Novartis Pharmaceuticals
- Study on Combining Radiation with Tarlatamab for DLL3 Expressing Tumors — University of Arizona
- Study on Using Radiotherapy to Prevent Cancer Growth in Metastatic Non-Small-Cell Lung Cancer — Canadian Cancer Trials Group
- Study on Using Stereotactic Body Radiation Therapy (SBRT) for Patients with Metastatic Breast and Lung Cancers — Memorial Sloan Kettering Cancer Center
- Study on Reduced Chemotherapy and Immunotherapy for Older Adults with Advanced Non-Small Cell Lung Cancer — Virginia Commonwealth University
- Study on the Safety and Effectiveness of Zimberelimab, Domvanalimab, and Etrumadenant for Previously Treated Non-Small Cell Lung Cancer — Washington University School of Medicine
- Study on the Safety and Early Effectiveness of BNT327 with Chemotherapy for Advanced Non-Small Cell Lung Cancer — BioNTech SE
- Study on the Safety and Tolerability of TNG456 Alone and with Abemaciclib in Patients with Solid Tumors with MTAP Loss — Tango Therapeutics, Inc.
- Study on the Safety and Effectiveness of BNT327 with Chemotherapy for Lung Cancer — BioNTech SE
- Study on the Effectiveness and Safety of Zimberelimab and Domvanalimab for Lung Cancer — Arcus Biosciences, Inc.
- Study on DPX-Survivac with Low Dose Cyclophosphamide and Pembrolizumab for Advanced and Recurrent Solid Tumors — ImmunoVaccine Technologies, Inc. (IMV Inc.)
- Study of CP-383 for Patients with Advanced or Metastatic Solid Tumors — Tasca Therapeutics
- Study on Daraxonrasib for Previously Treated Patients with RAS Mutated Non-Small Cell Lung Cancer (NSCLC) — Revolution Medicines, Inc.
- Study Comparing DS-1062a and Docetaxel for Advanced Non-Small Cell Lung Cancer — Daiichi Sankyo
- Study on Healthy Donor FMT and Pembrolizumab for Relapsed/Refractory PD-L1 Positive Lung Cancer — Diwakar Davar
- Study Comparing Izalontamab Brengitecan with Standard Chemotherapy for EGFR-Mutated Non-Small Cell Lung Cancer After EGFR TKI Therapy Failure — Bristol-Myers Squibb
- Study Comparing JDQ443 and Docetaxel for Advanced KRAS G12C Mutant Non-Small Cell Lung Cancer — Novartis Pharmaceuticals
- Study of Osimertinib With and Without Ramucirumab in Advanced Non-Small Cell Lung Cancer — Xiuning Le
- Study Comparing Subcutaneous and Intravenous Pembrolizumab with Chemotherapy for Advanced Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study Comparing Sacituzumab Govitecan and Docetaxel for Advanced Non-Small Cell Lung Cancer — Gilead Sciences
- Study of STK-012 Alone and With Other Treatments for Advanced Lung Cancer and Other Cancers — Synthekine
- Study on Telisotuzumab Vedotin for Previously Treated c-Met+ Non-Small Cell Lung Cancer — AbbVie
- Study on Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy for First-time Treatment of HER2 Overexpressing Non-small Cell Lung Cancer — Daiichi Sankyo
- Study on Atezolizumab Compared to Best Supportive Care After Chemotherapy in Lung Cancer Patients [IMpower010] — Hoffmann-La Roche
- Study on Firmonertinib vs. Other EGFR Inhibitors for Advanced Non-Small Cell Lung Cancer with Uncommon Mutations — ArriVent BioPharma, Inc.
- Symbiotic-Lung-10: Study on PF-08634404 Alone or with Chemotherapy for Early-stage or Locally Advanced Non-Small Cell Lung Cancer (NSCLC) — Pfizer
- Study on PF-08634404 with Other Cancer Medicines for Advanced Cancers — Pfizer
- Study on How the Combination of Sigvotatug Vedotin and Pembrolizumab Works in People with Non-Small Cell Lung Cancer with High PD-L1 Levels — Pfizer
- Study on Trabedersen (OT-101) and Pembrolizumab for Newly Diagnosed Advanced Non-Small Cell Lung Cancer with Positive PD-L1 — University of Nebraska
- Study on SPEDOX-6 for Advanced Cancers — University of California, Irvine
- Study on TT-10 and TT-4 as Single Agents and in Combination for Advanced Solid Tumors — Portage Biotech
- Study on Using High Dose Radiation Followed by Chemotherapy and Radiation for Treating Locally Advanced Non-Small Cell Lung Cancer (NSCLC) — Wake Forest University Health Sciences
- Study on VMD-928 Alone and with Pembrolizumab for Treating Solid Tumors or Lymphoma with High TrkA Levels — VM Oncology, LLC
- Study on Volrustomig with Other Cancer Drugs for Advanced Non-Small Cell Lung Cancer — AstraZeneca
- Study Comparing Zimberelimab and Domvanalimab with Chemotherapy to Pembrolizumab with Chemotherapy in Patients with Untreated Metastatic Non-Small Cell Lung Cancer — Gilead Sciences
- Study on Pembrolizumab and Berahyaluronidase Alfa for Treating Newly Diagnosed Metastatic Non-Small Cell Lung Cancer — Merck Sharp & Dohme LLC
- Study on EMB-01 Dose Escalation and Expansion for Adults with Advanced or Metastatic Solid Tumors — Shanghai EpimAb Biotherapeutics Co., Ltd.
- Global Study on Rilvegostomig or Pembrolizumab with Chemotherapy for First-Line Treatment of Metastatic Squamous Non-Small Cell Lung Cancer — AstraZeneca
- Global Study on Durvalumab and Domvanalimab After Chemoradiation for Stage III Unresectable Non-Small Cell Lung Cancer (NSCLC) — AstraZeneca
- Global Study on Durvalumab with Oleclumab or Monalizumab After Chemoradiation for Stage III Unresectable Non-Small Cell Lung Cancer — AstraZeneca
- Global Study on Osimertinib for Patients with Early-Stage EGFR-Mutated Non-Small Cell Lung Cancer After Tumor Removal — AstraZeneca
- A Phase 1/2 Study of DCC-3116 in Patients With RAS/MAPK Pathway Mutant Solid Tumors — Deciphera Pharmaceuticals, LLC
- Study on MRTX0902 for Treating Solid Tumors with KRAS MAPK Pathway Mutations — Mirati Therapeutics Inc.
- Study on CLN-081 for Patients with Non-Small Cell Lung Cancer — Cullinan Therapeutics Inc.
- Study on TC-510 Cell Therapy for Advanced Cancers with Mesothelin Expression — TCR2 Therapeutics
- Phase 2 Study of Adding Vitamin C to Chemotherapy and Radiation for Non-Small Cell Lung Cancer — Joseph J. Cullen, MD, FACS
- Study Comparing Sotorasib and Durvalumab for Non-Small Cell Lung Cancer (NSCLC) — Memorial Sloan Kettering Cancer Center
- Study on FMC-376 for Patients with KRAS G12C Mutated Advanced Solid Tumors — Frontier Medicines Corporation
- Study Comparing Divarasib with Sotorasib or Adagrasib for Treating Advanced KRAS G12C-positive Lung Cancer — Hoffmann-La Roche
- Study on the Effectiveness and Safety of Different Treatments for Stage III Non-Small Cell Lung Cancer — Hoffmann-La Roche
Looking for a program not shown above? Search the full catalog for “Non-Small-Cell Lung Cancer” to see every match including additional filters.
About this hub
Expanded access programs (sometimes called compassionate use, named-patient programs, or pre-approval access) allow patients with serious or life-threatening conditions such as Non-Small-Cell Lung Cancer to receive an investigational therapy outside of a controlled clinical trial when no comparable approved option is available. Eligibility, location, and the application process differ for each program — review the individual program pages below for sponsor contact information, inclusion criteria, and the request workflow. Right2Hope is a 501(c)(3) nonprofit and provides this directory free of charge for patients, caregivers, and treating physicians.
Looking for a different condition? Browse the full Cancer Type hub directory or search the full expanded access program catalog.
