Acute Myeloid Leukemia — Expanded Access Programs
Overview
Right2Hope maintains a directory of 131 expanded access programs, clinical trials, and compassionate use pathways listed for Acute Myeloid Leukemia. Each entry below was sourced from sponsor disclosures and public clinical-trial registries. Use this hub to understand the breadth of ongoing research, identify sponsors with acute myeloid leukemia programs, and link out to specific protocols for eligibility, contact, and request details. Of these, 105 programs are currently active or recruiting, with the remaining 26 in other lifecycle stages. Sponsors actively running programs in this area include M.D. Anderson Cancer Center, National Cancer Institute (NCI), Fred Hutchinson Cancer Center, Masonic Cancer Center, University of Minnesota, City of Hope Medical Center, and others.
By recruiting status
Snapshot of where every Acute Myeloid Leukemia program currently sits in its lifecycle.
- Active / Recruiting105
- Draft1
- Inactive25
Top sponsors
Organisations running the most Acute Myeloid Leukemia programs in the directory.
- M.D. Anderson Cancer Center21 programs
- National Cancer Institute (NCI)16 programs
- Fred Hutchinson Cancer Center8 programs
- Masonic Cancer Center, University of Minnesota5 programs
- City of Hope Medical Center4 programs
- AbbVie3 programs
- Memorial Sloan Kettering Cancer Center3 programs
- Taiho Oncology, Inc.3 programs
- University of Colorado, Denver3 programs
- University of Florida3 programs
Acute Myeloid Leukemia programs (showing 120 of 131)
Sorted by recruiting status, then alphabetically by program name. Click any program to view eligibility, locations, and sponsor contact details.
- Study on 211^At-BC8-B10 Before Donor Stem Cell Transplant for High-Risk Leukemia and Related Conditions — Fred Hutchinson Cancer Center
- Phase II Study on Dual Inhibition of BCL2 and Menin in AML Using Venetoclax and Revumenib — M.D. Anderson Cancer Center
- Study on Oral Combination Treatment for Acute Myeloid Leukemia (AML) — M.D. Anderson Cancer Center
- Pilot Study on Using Decitabine and Filgrastim After Stem Cell Transplant in Children and Young Adults with Blood Cancers — Franziska Wachter
- Study for Participants Continuing ASTX727 Treatment from Previous Clinical Trials — Taiho Oncology, Inc.
- Study of ASTX030 (Cedazuridine and Azacitidine) for MDS, CMML, or AML — Taiho Oncology, Inc.
- A Study of BGB-11417 in Participants With Myeloid Malignancies — BeiGene
- A Study of CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMML — Treadwell Therapeutics, Inc
- Study on CTX-712 for Treating Relapsed or Hard-to-Treat Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes — Chordia Therapeutics, Inc.
- Study on Revumenib and Mezigdomide for Treating Leukemia — Memorial Sloan Kettering Cancer Center
- Study on Revumenib for Treating Relapsed or Refractory Leukemias with Specific Gene Changes — Syndax Pharmaceuticals
- Study on Tagraxofusp with Venetoclax and Azacitidine for Adults with Untreated CD123+ Acute Myeloid Leukemia Who Cannot Have Intensive Chemotherapy — Stemline Therapeutics, Inc.
- Study on the Combination of Ivosidenib, Azacitidine, and Venetoclax Followed by Ivosidenib Alone for Treating Acute Myeloid Leukemia — Memorial Sloan Kettering Cancer Center
- Study on Venetoclax with Chemotherapy for Children with Acute Myeloid Leukemia — St. Jude Children's Research Hospital
- Study on the Safety and Effects of Pivekimab Sunirine with Venetoclax and Azacitidine for Treating Acute Myeloid Leukemia (AML) — AbbVie
- Study on the Safety and Effectiveness of Bexmarilimab Combined with Standard Treatment for Blood Cancers — Faron Pharmaceuticals Ltd
- Study on the Safety and Effectiveness of Debio 1562M for Treating Acute Myeloid Leukemia (AML) — Debiopharm International SA
- Study Comparing Standard Chemotherapy to CPX-351 and/or Gilteritinib for Newly Diagnosed Acute Myeloid Leukemia (AML) with or without FLT3 Mutations — Children's Oncology Group
- Study Comparing Oral Azacitidine Plus Supportive Care to Supportive Care Alone for Maintenance Therapy in Japanese Patients with Acute Myeloid Leukemia in Complete Remission — Bristol-Myers Squibb
- Study on Depleting Alpha/Beta T Cells and CD19+ B Cells in Stem Cell Transplants for Patients with Blood Cancers — University of Florida
- Extension Study for Patients Continuing Venetoclax Treatment from Previous Trials — AbbVie
- Study on ASTX727, Venetoclax, and Gilteritinib for Treating FLT3-Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome — M.D. Anderson Cancer Center
- Study on Azacitidine and Venetoclax as Ongoing Treatment for Patients with Acute Myeloid Leukemia in Remission — M.D. Anderson Cancer Center
- Study on Azacitidine and Enasidenib for Treating Patients with IDH2-Mutant Myelodysplastic Syndrome — M.D. Anderson Cancer Center
- Study on Azacitidine and Gemtuzumab Ozogamicin for Older Patients with Untreated Acute Myeloid Leukemia — National Cancer Institute (NCI)
- Study on Azacitidine or Decitabine with Venetoclax for Acute Myeloid Leukemia After Previous Treatment Failure — Brian Jonas
- Study on Adding Pembrolizumab to Standard Chemotherapy for Treating Acute Myeloid Leukemia — National Cancer Institute (NCI)
- Study on Bleximenib with Standard Chemotherapy for Treating Acute Myeloid Leukemia (AML) — Stichting Hemato-Oncologie voor Volwassenen Nederland
- Study on Chemotherapy and Total-Body Radiation Followed by Donor Stem Cell Transplant for Treating High-Risk Myeloid Cancers — Fred Hutchinson Cancer Center
- Study on Cladribine and Venetoclax for Treating Monocytic Acute Myeloid Leukemia (AML) — University of Colorado, Denver
- Study on Cladribine, Idarubicin, Cytarabine, and Quizartinib for Treating Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome — M.D. Anderson Cancer Center
- Study on Cladribine, Idarubicin, Cytarabine, and Venetoclax for Treating Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia — M.D. Anderson Cancer Center
- Study on Chemotherapy and Radiation Therapy Followed by Donor Cell Transplant for Treating Older Adults with High-Risk Acute Myeloid Leukemia or Other Severe Blood Cancers — Fred Hutchinson Cancer Center
- Comparing Different Drug Combinations for Treating Younger Patients with Intermediate Risk Acute Myeloid Leukemia (AML) — National Cancer Institute (NCI)
- Study Comparing Different Treatment Durations of Venetoclax for Older Adults with Newly Diagnosed Acute Myeloid Leukemia — National Cancer Institute (NCI)
- Comparing New Treatments for Newly Diagnosed Acute Myeloid Leukemia with an IDH2 Gene Mutation — National Cancer Institute (NCI)
- Study on Adding Pomalidomide to Standard Chemotherapy for Newly Diagnosed Acute Myeloid Leukemia with Myelodysplastic Syndrome-Related Changes — National Cancer Institute (NCI)
- Study on Cord Blood Transplant with Chemotherapy and Radiation for Treating High-Risk Blood Diseases — Fred Hutchinson Cancer Center
- Study on Memory-like NK Cell Therapy After Partial Match Donor Stem Cell Transplant — Washington University School of Medicine
- Study on Cytokine-Induced Memory-Like Natural Killer Cells for Treating Relapsed or Hard-to-Treat Acute Myeloid Leukemia — Children's Hospital Medical Center, Cincinnati
- Study on Cytokine-Treated Veto Cells for Patients with Blood Cancers After Stem Cell Transplant — M.D. Anderson Cancer Center
- Study on Daunorubicin and Cytarabine With or Without Uproleselan for Treating Older Adults with Acute Myeloid Leukemia — National Cancer Institute (NCI)
- Study on Decitabine and Venetoclax as Maintenance Therapy After Stem Cell Transplant for Blood Cancer Patients — Benjamin Tomlinson
- Study on Decitabine with Ruxolitinib, Fedratinib, or Pacritinib for Treating Advanced Myeloproliferative Neoplasms — University of Washington
- Study on Decitabine, Cytarabine, and Daunorubicin for Treating Acute Myeloid Leukemia — National Cancer Institute (NCI)
- Study on Decitabine/Cedazuridine and Venetoclax with Ivosidenib or Enasidenib for Treating Relapsed or Resistant Acute Myeloid Leukemia — M.D. Anderson Cancer Center
- Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers — M.D. Anderson Cancer Center
- Study on Stopping Chemotherapy in Patients with Acute Myeloid Leukemia (AML) in Remission — H. Lee Moffitt Cancer Center and Research Institute
- Donor Stem Cell Transplant with Treosulfan, Fludarabine, and Total-Body Irradiation for Treating Blood Cancers — Fred Hutchinson Cancer Center
- Study on Donor-Derived Natural Killer Cell Infusions for Children and Young Adults with High-Risk Acute Myeloid Leukemia Undergoing Transplant — Michael Pulsipher
- Study on Two Different Doses of Quizartinib for Maintenance in Acute Myeloid Leukemia Patients in Complete Remission — Daiichi Sankyo
- Expanded Access Program for Galinpepimut-S in Patients with AML or MDS — Sellas Life Sciences Group
- First Human Study of Ziftomenib for Treating Relapsed or Hard-to-Treat Acute Myeloid Leukemia — Kura Oncology, Inc.
- Study on Using FLT PET/CT Scans to Measure Treatment Response in Patients with Untreated Acute Myeloid Leukemia — National Cancer Institute (NCI)
- Study on Fractionated Gemtuzumab Ozogamicin for Treating Residual Disease in Acute Myeloid Leukemia Patients — University of Washington
- Study Comparing Galinpepimut-S to Best Available Therapy for Maintenance in Acute Myeloid Leukemia (AML) in Second Remission — Sellas Life Sciences Group
- Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS) — Fred Hutchinson Cancer Center
- Study on HLA-Mismatched Unrelated Donor Stem Cell Transplant with Reduced Cyclophosphamide for Graft Versus Host Disease Prevention — Center for International Blood and Marrow Transplant Research
- Study on Different Treatment Orders for Newly Diagnosed IDH Mutated AML Patients Not Suitable for Intensive Therapy — Alice Mims
- Study on Improving Risk Assessment in AML Using Precision Genomic Strategy to Check Mutation Clearance — Washington University School of Medicine
- Study on Using Fludarabine, Cytarabine, Idarubicin, and Venetoclax for Treating Acute Myeloid Leukemia — OHSU Knight Cancer Institute
- Using Interferon-γ and Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes After Stem Cell Transplant — Sawa Ito, MD
- Study on Ivosidenib and Venetoclax With or Without Azacitidine for Treating Blood Cancers with IDH1 Mutation — M.D. Anderson Cancer Center
- Ivosidenib Access Program for Patients with Relapsed or Hard-to-Treat AML with an IDH1 Mutation — Agios Pharmaceuticals, Inc.
- Study on Using KIR-Favorable Donors for Transplants in Children with Certain Blood Cancers — Michael Pulsipher
- Study on Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for Treating Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome — M.D. Anderson Cancer Center
- Study on Low Dose Weekly Decitabine and Venetoclax for Treating MDS and AML — Montefiore Medical Center
- Comparing Stem Cell Transplant Options for Young People with Acute Leukemia or Myelodysplastic Syndrome — Children's Oncology Group
- Study on T Cell Receptor Alpha/Beta Depletion Stem Cell Transplant for Blood Cancers — Masonic Cancer Center, University of Minnesota
- Study on Using Reduced Intensity Conditioning and Stem Cell Transplant for Treating Blood Diseases — Masonic Cancer Center, University of Minnesota
- Study on Myeloablative Stem Cell Transplant with Donor for Blood Disorders — Masonic Cancer Center, University of Minnesota
- MYELOMATCH: Screening Study for Myeloid Cancer Treatment Options — National Cancer Institute (NCI)
- Study on Olutasidenib and Azacitidine for Treating IDH1-Mutated Acute Myeloid Leukemia After Previous Treatment — University of California, Davis
- Study on Olutasidenib, Venetoclax, and Azacitidine for Newly Diagnosed Acute Myeloid Leukemia with IDH1 Mutation — Justin Watts, MD
- Study on Oral Azacitidine for Transplant-Eligible Patients with Acute Myeloid Leukemia Facing Health Inequality — Virginia Commonwealth University
- Study on the Safety and Effectiveness of ASTX727 and Venetoclax for Treating Acute Myeloid Leukemia (AML) — Taiho Oncology, Inc.
- Study on Proteasome Inhibitor and CPX-351 for Treating Newly-Diagnosed TP53-Mutated Acute Myeloid Leukemia (AML) — Masonic Cancer Center, University of Minnesota
- Pilot Study of Memory-like Natural Killer Cells After Half-Matched Family Stem Cell Transplant in High-Risk Acute Myeloid Leukemia — Washington University School of Medicine
- Study on Orca-T for Patients Undergoing Stem Cell Transplant for Blood Cancers — Orca Biosystems, Inc.
- Study on Reduced-Intensity Conditioning to Lower Treatment-Related Deaths in Patients Undergoing Stem Cell Transplant — Thomas Jefferson University
- Ruxolitinib + Allogeneic Stem Cell Transplantation in AML — Massachusetts General Hospital
- Study on Ruxolitinib with Tacrolimus and Methotrexate to Prevent Graft Versus Host Disease in Young Patients Undergoing Bone Marrow Transplant for Leukemia or Myelodysplastic Syndrome — City of Hope Medical Center
- Safety and Efficacy of Expanded, Universal Donor Natural Killer Cells for Relapsed/Refractory AML — Nationwide Children's Hospital
- Study on the Safety and Effectiveness of Quizartinib for Children and Young Adults with Acute Myeloid Leukemia (AML) — Daiichi Sankyo
- Study on Using Intensity Modulated Total Marrow Irradiation with Fludarabine/Busulfan for Transplant in High-Risk AML and Myelodysplastic Syndromes — University of Illinois at Chicago
- Study on CCS1477 for Blood Cancers — CellCentric Ltd.
- Study on Tagraxofusp and Azacitidine With or Without Venetoclax for Newly Diagnosed Secondary AML After Previous Treatment — Joshua Zeidner
- Study on Using Nivolumab to Prevent Acute Myeloid Leukemia from Returning After Treatment — National Cancer Institute (NCI)
- Study on Oral Decitabine and Cedazuridine (ASTX727) with Venetoclax for Higher-Risk Acute Myeloid Leukemia Patients — National Cancer Institute (NCI)
- Testing New Treatments for Newly Diagnosed, Untreated Patients with High-Risk Acute Myeloid Leukemia (AML) — National Cancer Institute (NCI)
- Study on Topotecan, Carboplatin, and Veliparib for Treating Advanced Blood Disorders and Leukemia — National Cancer Institute (NCI)
- Study on Total Marrow and Lymphoid Irradiation Before Stem Cell Transplant for Patients with Myelodysplastic Syndrome or Acute Leukemia — City of Hope Medical Center
- Study on MGTA-456 for Patients with High-Risk Cancer — Masonic Cancer Center, University of Minnesota
- Study on Vedolizumab, Cyclophosphamide, and Tacrolimus to Prevent Graft Versus Host Disease in Patients Undergoing Stem Cell Transplant — City of Hope Medical Center
- Study Comparing Venetoclax and Azacitidine with Standard Chemotherapy in Acute Myeloid Leukemia (AML) — Massachusetts General Hospital
- Venetoclax and ASTX727 for the Treatment of Relapsed, Refractory, or Newly Diagnosed Acute Myeloid Leukemia — M.D. Anderson Cancer Center
- Study on Venetoclax and Azacitidine for Treating Acute Myeloid Leukemia After Stem Cell Transplant — M.D. Anderson Cancer Center
- Study on Venetoclax and CLAG-M for Treating Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms — University of Washington
- Study on Venetoclax and HMA Treatment for Older Adults with FLT3 Mutated Acute Myeloid Leukemia (AML) — National Cancer Institute (NCI)
- Study on Venetoclax and Chemotherapy Before Donor Stem Cell Transplant for Treating Acute Myelogenous Leukemia or Myelodysplastic Syndrome — M.D. Anderson Cancer Center
- Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML) — LLS PedAL Initiative, LLC
- Study on Venetoclax with Cladribine, Cytarabine, and Azacitidine for Newly Diagnosed Monocytic AML and Mutated AML — OHSU Knight Cancer Institute
- Study on Venetoclax to Improve Outcomes of Chemotherapy in Patients with High-Risk Acute Myeloid Leukemia and Myelodysplastic Syndrome — M.D. Anderson Cancer Center
- Study on Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine for Treating Untreated Acute Myeloid Leukemia — M.D. Anderson Cancer Center
- Ziftomenib for Treating Acute Myeloid Leukemia with NPM1 Mutation or KMT2A Rearrangement in Patients Not Eligible for Standard Therapy — Uma Borate
- Orca-T Expanded Access Program Study for Patients With Advanced Hematologic Malignancies — Orca Biosystems, Inc.
- Study on Bleximenib for Patients with Acute Leukemia — Janssen Research & Development, LLC
- Study on the Safety and Effectiveness of CTX131 for Adults with Difficult-to-Treat Blood Cancers — CRISPR Therapeutics
- Study on APG-115 Alone or Combined with Azacitidine for Patients with AML, CMML, or MDS — Ascentage Pharma Group Inc.
- Study Comparing Azacitidine and Venetoclax with Stem Cell Transplant in People Aged 65 and Older with Acute Myeloid Leukemia — Memorial Sloan Kettering Cancer Center
- A Study to Investigate Natural Killer Cell Engager (SAR443579) With Different Agents in Participants With Hematological Malignancies — Sanofi
- Study on Two Schedules of MS275 and 5AC for Treating Acute Myeloid Leukemia in Older Adults — Hetty Carraway
- Study on Azacitidine and Venetoclax for Initial Treatment and Maintenance in Elderly Patients with Acute Myeloid Leukemia (AML) — University of Colorado, Denver
- Study on Bortezomib and Sorafenib Tosylate for Newly Diagnosed Acute Myeloid Leukemia — National Cancer Institute (NCI)
- Study on CPX-351 or CLAG-M Treatment for Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms in Less-Fit Patients — Fred Hutchinson Cancer Center
- Study on DEC-C and Thioguanine for Relapsed or Refractory Acute Myeloid Leukemia (AML) — Joseph Jurcic
- Study on Decitabine, Venetoclax, and Ponatinib for Treating Philadelphia Chromosome-Positive Leukemia — M.D. Anderson Cancer Center
- Study on Cladribine-Based Chemotherapy for Treating Relapsed or Hard-to-Treat Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome — Medical College of Wisconsin
- Study on Enasidenib Maintenance Therapy After Stem Cell Transplant in Patients with IDH2 Mutation — City of Hope Medical Center
- Access to ABBV-787 Before Official Approval — AbbVie
Looking for a program not shown above? Search the full catalog for “Acute Myeloid Leukemia” to see every match including additional filters.
About this hub
Expanded access programs (sometimes called compassionate use, named-patient programs, or pre-approval access) allow patients with serious or life-threatening conditions such as Acute Myeloid Leukemia to receive an investigational therapy outside of a controlled clinical trial when no comparable approved option is available. Eligibility, location, and the application process differ for each program — review the individual program pages below for sponsor contact information, inclusion criteria, and the request workflow. Right2Hope is a 501(c)(3) nonprofit and provides this directory free of charge for patients, caregivers, and treating physicians.
Looking for a different condition? Browse the full Cancer Type hub directory or search the full expanded access program catalog.
