Study on Stereotactic Radiosurgery for Lung Cancer That Has Spread to the Brain
Sponsor: Memorial Sloan Kettering Cancer Center
Sponsor score: 60
ClinicalTrials ID:NCT05419076
This clinical trial is exploring whether a precise form of radiation therapy, called stereotactic radiosurgery (SRS), is effective for treating people whose small cell lung cancer has spread to the brain.
Patient Parameters
| Parameter | Options |
|---|
Program Overview
The aim of this study is to determine if stereotactic radiosurgery (SRS) is a successful treatment option for patients who have been newly diagnosed with brain metastases resulting from small cell lung cancer (SCLC).
Eligibility Criteria
Inclusion Criteria
- Diagnosed with small cell lung cancer.
- Have up to 10 brain tumors as seen on a special MRI scan.
- Aged 18 years or older.
- In good enough health to perform daily activities, with a performance status score between 60 and 100 on the KPS scale or 0 to 2 on the ECOG scale.
- Female participants must either not be able to become pregnant or have a negative pregnancy test before joining the study.
- Able to give informed consent, or have a legally authorized representative who can do so.
Exclusion Criteria
- Cannot have an MRI scan with contrast dye for the brain or spine.
- Have cancer spread to the lining of the brain or spinal cord, confirmed by specific tests.
- Pregnant or breastfeeding women cannot participate.
- Have had previous radiation treatment directed at the brain.
- Have uncontrolled disease elsewhere in the body that is likely to lead to death within three months, as shown by recent CT or PET/CT scans.
Locations
| FACILITY | ZIP | CITY | STATE |
|---|---|---|---|
| Hartford Healthcare (Data Collection Only) | 06102 | Hartford | Connecticut |
| Memorial Sloan Kettering at Basking Ridge | 07920 | Basking Ridge | New Jersey |
| Memorial Sloan Kettering Monmouth | 07748 | Middletown | New Jersey |
| Memorial Sloan Kettering Bergen | 07645 | Montvale | New Jersey |
| Memorial Sloan Kettering Suffolk - Commack | 11725 | Commack | New York |
| Memorial Sloan Kettering Westchester | 10604 | Harrison | New York |
| Memorial Sloan Kettering Cancer Center (All Protocol Activities) | 10065 | New York | New York |
| Memorial Sloan Kettering Nassau | 11553 | Rockville Centre | New York |
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