Study on Stereotactic Radiosurgery for Lung Cancer That Has Spread to the Brain

Sponsor: Memorial Sloan Kettering Cancer Center

Sponsor score: 60
Inactive

ClinicalTrials ID:NCT05419076

This clinical trial is exploring whether a precise form of radiation therapy, called stereotactic radiosurgery (SRS), is effective for treating people whose small cell lung cancer has spread to the brain.

Patient Parameters

Program Overview

The aim of this study is to determine if stereotactic radiosurgery (SRS) is a successful treatment option for patients who have been newly diagnosed with brain metastases resulting from small cell lung cancer (SCLC).

Eligibility Criteria

Inclusion Criteria

  • Diagnosed with small cell lung cancer.
  • Have up to 10 brain tumors as seen on a special MRI scan.
  • Aged 18 years or older.
  • In good enough health to perform daily activities, with a performance status score between 60 and 100 on the KPS scale or 0 to 2 on the ECOG scale.
  • Female participants must either not be able to become pregnant or have a negative pregnancy test before joining the study.
  • Able to give informed consent, or have a legally authorized representative who can do so.

Exclusion Criteria

  • Cannot have an MRI scan with contrast dye for the brain or spine.
  • Have cancer spread to the lining of the brain or spinal cord, confirmed by specific tests.
  • Pregnant or breastfeeding women cannot participate.
  • Have had previous radiation treatment directed at the brain.
  • Have uncontrolled disease elsewhere in the body that is likely to lead to death within three months, as shown by recent CT or PET/CT scans.

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