Radiation Therapy Approaches for People With Prostate Cancer
Sponsor: Memorial Sloan Kettering Cancer Center
Sponsor score: 60
ClinicalTrials ID:NCT07751159
This study evaluates optimal radiation therapy methods for non-metastatic prostate cancer patients at unfavorable intermediate to very high risk. Eligible participants must be suitable for both HDR brachytherapy boost and SBRT. Interventions include standard brachytherapy and SBRT alone, aiming to balance cancer control with minimizing side effects.
Patient Parameters
| Parameter | Options |
|---|
Program Overview
The purpose of the study is to explore the best ways of giving radiation therapy to balance cancer control and treatment side effects.
Eligibility Criteria
Inclusion Criteria
- Non-metastatic prostate cancer.
- Classified as unfavorable intermediate-, high-, or very high-risk prostate cancer according to NCCN risk stratification guidelines. (Note: cT3a or T3b by MRI or PSMA PET allowed)
- Considered by the treating radiation oncologist as a suitable candidate for both HDR brachytherapy boost and SBRT (see clinical considerations for treatment eligibility below)
Exclusion Criteria
- None
Locations
| FACILITY | ZIP | CITY | STATE |
|---|---|---|---|
| Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities) | 07920 | Basking Ridge | New Jersey |
| Memorial Sloan Kettering at Monmouth (Limited Protocol Activities) | 07748 | Middletown | New Jersey |
| Memorial Sloan Kettering at Bergen (Limited Protocol Activities) | 07645 | Montvale | New Jersey |
| Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities) | 11725 | Commack | New York |
| Memorial Sloan Kettering at Westchester (Limited Protocol Activities) | 10604 | Harrison | New York |
| Memorial Sloan Kettering Cancer Center (All Protocol Activites) | 10065 | New York | New York |
| Memorial Sloan Kettering at Nassau (Limited Protocol Activities) | 11553 | Uniondale | New York |
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