Study on 64Cu-SAR-bisPSMA PET/CT for Detecting Prostate Cancer Recurrence

Inclusion Criteria

• Must be at least 18 years old.
• Must provide signed consent to participate.
• Must have a life expectancy of at least 6 months, as assessed by the study doctor.
• Must have a confirmed diagnosis of prostate cancer and have completed initial treatment.
• Must be eligible for additional treatment aimed at curing the cancer.
• Must have specific PSA levels indicating potential cancer recurrence:
  • After prostate removal surgery: PSA level of 0.2 ng/mL or higher, confirmed by a second test.
  • After radiation, cryotherapy, or brachytherapy: PSA level increased by 2 ng/mL or more above the lowest level recorded.
• Must be willing to have a biopsy of any suspicious areas found by the PET scan, if safe to do so.
• Must have a performance status score of 0 to 2, indicating good overall health.

Exclusion Criteria

• Have received an experimental treatment within a certain time frame before starting the study.
• Have been given any high-energy radioactive substances recently.
• Have had previous systemic treatment for prostate cancer, except for certain therapies given as part of initial treatment.
• Are currently receiving or have recently received any systemic treatment for prostate cancer, including hormone therapies, chemotherapy, or radiation.
• Have known allergies to the imaging agent used in the study.
• Have any serious medical conditions or other circumstances that might interfere with the study procedures or evaluations.