Study on IPG7236 for Patients with Advanced Solid Tumors

Inclusion Criteria

• Must be 18 years or older.
• Have a confirmed diagnosis of advanced or recurrent solid tumors that cannot be surgically removed.
• Must have tried standard treatments for their cancer type without success or cannot tolerate them.
• Must have measurable disease according to specific criteria.
• Must have a life expectancy of at least 3 months.
• Must be in good overall health with a performance status score of 0 or 1.
• Must have adequate blood and organ function based on specific lab tests.
• Must be able to swallow pills and follow study requirements.
• Women of childbearing potential must have a negative pregnancy test and use effective birth control.
• Men with partners of childbearing potential must use effective birth control or be surgically sterile.

Exclusion Criteria

• Have cancer of the central nervous system or related to HIV or organ transplant.
• Have not recovered from side effects of previous cancer treatments.
• Have had recent cancer treatments or major surgery within specified timeframes.
• Have uncontrolled diseases or active infections that could affect the study.
• Have positive COVID-19 tests unless cleared by the investigator.
• Have received live vaccines recently or plan to during the study.
• Have active hepatitis B or C, or uncontrolled HIV.
• Have had another cancer within the last 3 years, with some exceptions.
• Have untreated or unstable brain or spinal cord metastases.
• Have digestive issues affecting drug absorption.
• Have heart rhythm issues or take medications affecting heart rhythm.
• Are pregnant or breastfeeding, or not using effective contraception if of childbearing potential.
• Cannot comply with study procedures.