Study on Using ICG Dye Imaging to Identify Tumor Margins During Surgery

Program Overview

The purpose of this study is to learn more about using a dye called indocyanine green (ICG) during surgeries to remove bone or soft tissue tumors. ICG is a dye used in medical tests, and researchers want to see if it helps surgeons remove tumors more completely. They will also look at how this affects the chances of cancer returning, spreading, and overall survival rates.

Description

If you have a pre-surgery clinic visit the day before your operation, you may receive an injection of ICG. If not, ICG will be given through an IV about 4 hours before your surgery. You will be monitored during and after receiving the ICG.

During the surgery, a special camera will be used to see the ICG dye in the tumor. This helps the surgeon make sure they are removing all of the tumor. After the main part of the tumor is removed, the surgeon will check the area to see if any cancerous tissue is left. If the camera shows any remaining cancer, the surgeon will try to remove it and send it for further testing.

The removed tumor and any additional samples will be examined under a microscope to check for cancer cells and how well the ICG dye worked. This involves looking at the samples with a special microscope to see if the dye correctly highlighted the cancer.

The tissue removed is small and from non-critical areas, so it should not affect your health or involve sensitive areas like nerves or blood vessels. This extra tissue helps ensure all cancer is removed.

Eligibility Criteria