Study on Palliative Radiation Therapy for Pain Relief in Metastatic Bone Disease

Sponsor: University of Cincinnati

Sponsor score: 0

ClinicalTrials ID:NCT05115331

Provider View

This clinical trial is testing two different radiation therapy approaches to see which is more effective in reducing pain and improving quality of life for patients with metastatic bone disease.

Patient Parameters

Program Overview

The study aims to find out if a new way of giving radiation therapy can better relieve pain and improve the quality of life for patients with metastatic bone disease. Patients will be randomly assigned to receive either the standard radiation treatment or a new experimental treatment. Both treatments aim to reduce pain and improve daily functioning.

Description

Metastatic Bone Disease (MBD) often causes severe pain and can affect a person's overall well-being. Radiation therapy is a common treatment to help relieve this pain. The standard treatment involves a single session of radiation, but this can sometimes lead to the need for more treatments later. This study is exploring whether a new method of giving radiation in two sessions can provide better and longer-lasting pain relief. The researchers believe that this new approach might help more patients feel better and for a longer time. Participants will be monitored for changes in pain levels and quality of life throughout the study.

Eligibility Criteria

Inclusion Criteria

  • Must have a confirmed diagnosis of a solid cancer that has spread to the bones.
  • Have 1 to 3 new or newly painful bone lesions as shown by scans.
  • Must have pain clearly linked to these bone lesions.
  • Be 18 years or older.
  • Be in relatively good health, able to perform daily activities with some limitations.
  • Have no other health conditions that would interfere with the study.
  • Be able to understand and agree to the study by signing a consent form.

Exclusion Criteria

  • Have had or will have chemotherapy within two weeks before starting the study treatment.
  • Have widespread cancer that makes it hard to identify the source of bone pain.
  • Be receiving other experimental treatments.
  • Have complicated bone issues like nerve compression or fractures.
  • Have had previous radiation or surgery to the bone area being studied.
  • Have uncontrolled health problems.
  • Be pregnant.
  • Have a life expectancy of less than three months.
  • Have blood cancers like myeloma or lymphoma.
  • Be considered unsuitable for the study by the investigator.

Get This Program In Your Inbox

Receive detailed information about this treatment opportunity to review with your healthcare provider.